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| resources:fluoroquinolones [2018/12/11 02:14] bpaddock Locally serve the News Net5 Video. | resources:fluoroquinolones [2018/12/14 02:15] bpaddock Updated PRAC formating. | ||
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| + | ====== European Medicines Agency’s (EMA) Pharmacovigilance Risk Assessment Committee (PRAC) has recommended restricting the use of fluoroquinolone and quinolone antibiotics ====== | ||
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| + | November 16 2018: | ||
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| + | serious side effects with a fluoroquinolone or quinolone antibiotic. They should be used with **special | ||
| + | caution** in the elderly, patients with kidney disease and those who have had an organ transplantation | ||
| + | because these patients are at a higher risk of tendon injury. //Since the use of a corticosteroid with a | ||
| + | fluoroquinolone also increases this risk, combined use of these medicines should be avoided// | ||
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| + | October 5th 2018: | ||
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| + | Press release 05/10/2018 [October 5th 2018] | ||
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| + | The European Medicines Agency’s (EMA) Pharmacovigilance Risk Assessment Committee (PRAC) has recommended restricting the use of fluoroquinolone and quinolone antibiotics (used by mouth, injection or inhalation) following a review of disabling and potentially long-lasting side effects reported with these medicines. The review incorporated the views of patients, healthcare professionals and academics presented at EMA’s public hearing on fluoroquinolone and quinolone antibiotics in June 2018. | ||
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| + | Very rarely [**//__THIS IS NOT TRUE, NOT RARE AT ALL__//**], patients treated with fluoroquinolone or quinolone antibiotics have suffered long-lasting and disabling side effects, mainly involving muscles, tendons and bones and the nervous system. | ||
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| + | The PRAC recommended that the remaining fluoroquinolone antibiotics should: | ||
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| + | **not** be used | ||
| + | * to treat infections that might get better without treatment or are not severe (such as throat infections); | ||
| + | for preventing traveller’s diarrhoea or recurring lower urinary tract infections (urine infections that do not extend beyond the bladder); | ||
| + | * to treat patients who have previously had serious side effects with a fluoroquinolone or quinolone antibiotic; | ||
| + | * to treat mild or moderately severe infections unless other antibacterial medicines commonly recommended for these infections cannot be used; | ||
| + | * be used with caution especially for the elderly [They should not be used in the elderly at all], patients with kidney problems, patients who have had an organ transplantation or those who are being treated with a systemic corticosteroid. These patients are at higher risk of tendon injury caused by fluoroquinolone and quinolone antibiotics. | ||
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| + | The PRAC also recommended that healthcare professionals should advise patients to stop treatment with a fluoroquinolone antibiotic at the first sign of a side effect involving muscles, tendons or bones (such as inflamed or torn tendon, muscle pain or weakness, and joint pain or swelling) or the nervous system (such as feeling pins and needles, tiredness, depression, confusion, suicidal thoughts, sleep disorders, vision and hearing problems, and altered taste and smell).</ | ||
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| + | June 13th 2018: | ||
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| + | [[https:// | ||
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| + | {{youtube> | ||
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| <WRAP important> | <WRAP important> | ||